Selected Publications

* Co-first authors, # Co-corresponding authors. For a full list of publications, please visit Google Scholar.

• J. H. Sussman*, D. A. Oldridge*, W. Yu*, et al. A longitudinal single-cell and spatial multiomic atlas of pediatric high-grade glioma Cell Reports Medicine (2026, in press).

• W. Yu*, R. Biyik-Sit*, Y. Uzun*, C.H. Chen*, A. Thadi, et al. Longitudinal single-cell multiomic atlas of high-risk neuroblastoma reveals chemotherapy-induced tumor microenvironment rewiring Nature Genetics (2025).

• A.U. Zezulin, D. Ye, E. Howell, D. Yen, E. Bresciani, J. Diemer, J. Ren, …, W. Yu#, N. A. Speck#. RUNX1 is required in granulocyte-monocyte progenitors to attenuate inflammatory cytokine production by neutrophils Genes & Development (2023).

• C. Chen, W. Yu*, F. Alikarami*, Q. Qiu, et al. Single-cell multiomics reveals increased plasticity, resistant populations, and stem-cell–like blasts in KMT2A-rearranged leukemia *Blood (2022).

• W. Yu, Y. Uzun, Q. Zhu, C. Chen, K. Tan. scATAC-pro: a comprehensive workbench for single-cell chromatin accessibility sequencing data Genome Biology (2020).

• C. Chen*, W. Yu*, J. Tober, P. Gao, B. He, K. Lee, T. Trieu, G.A. Blobel, et al. Spatial genome re-organization between fetal and adult hematopoietic stem cells Cell Reports (2019).

• W. Yu, J.K. Kim, T. Park. Estimation of Area Under the ROC Curve under nonignorable verification bias Statistica Sinica (2018).

• W. Yu, B. He, K. Tan. Identifying topologically associating domains and subdomains by Gaussian Mixture model And Proportion test Nature Communications (2017).

• W. Yu, S. Lee, T. Park. A unified model based multifactor dimensionality reduction framework for detecting gene–gene interactions Bioinformatics (2016).

• W. Yu, T. Park. Comparison of paired ROC curves through a two-stage test Journal of Biopharmaceutical Statistics (2015).

• W. Yu, T. Park. Two simple algorithms on linear combination of multiple biomarkers to maximize partial area under the ROC curve Computational Statistics & Data Analysis (2015).

• W. Yu*, M.S. Kwon*, T. Park. Multivariate quantitative multifactor dimensionality reduction for detecting gene-gene interactions Human Heredity (2015).

• W. Yu, T. Park. AucPR: an AUC-based approach using penalized regression for disease prediction with high-dimensional omics data BMC Genomics (2014).

• W. Yu, Y. Ivan Chang, E. Park. A modified area under the ROC curve and its application to marker selection and classification Journal of the Korean Statistical Society (2014).